Courteney Cox and Lisa Kudrow are not friends on new TV show 'Cougar Town'.
Lisa - who played Pheobe Buffay in 'Friends' alongside Courteney's Monica Geller - stars as a mean dermatologist in the series who treats Courteney's character Jules.
'Cougar Town' executive producer Bill Lawrence said: "They didn't want to play friends.
"Lisa plays a dermatologist who is a horrible, horrible person, but Courteney goes to her because she's the best.
"The sight of them playing people who dislike each other intensely was very funny for me to watch."
Lisa's character Dr Amy Evans has a reputation as one of the best doctors in town with a very harsh manner.
The cameo scene sees Dr Evans inject Jules with Botox after prodding and pulling her face.
'Cougar Town' follows the story of Jules, a recently divorced 40-something who is looking for some excitement in her life.