The supermodel - who has children Leni, five, Henry, four, Johan, three, and Lou, four months - insists she is too devoted to her singer husband Seal to even look at another man.
50 Cent wants to collaborate with Scottish singer Susan Boyle.
The rapper is a huge fan of the 'Britain's Got Talent' runner-up - whose debut album 'I Dreamed A Dream' has topped the album charts in both the UK and US - and would like to duet with her.
Seal wants to adopt Heidi Klum's daughter before Christmas.
The 'Kiss From A Rose' singer is keen to take legal guardianship of five-year-old Leni - his wife's daughter from her relationship with Formula One boss Flavio Briatore - and has already begun the legal proceedings.