Dermot Mulroney has filed for divorce from Catherine Keener after nearly 17 years of marriage and two years of separation.

The acclaimed actors married in 1990 and separated in 2005. They have a seven-year-old son, Clyde.

Dermot, who has starred in "About Schmidt" and "My Best Friend's Wedding," cited "irreconcilable differences" when divorcing his wife.

Catherine has been nominated for two Academy Awards and was a close friend of Brad Pitt and Jennifer Aniston's during their marriage.

Dermot and Catherine co-starred together in 2001's "Lovely And Amazing."

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